I can't live without my Labello...especially the med protection one.
I always have about two laying around at all times, mostly because I always misplace one.
I find that the Med Protection locks in moisture better than any other labello, it also doesn't leave a shine behind (great for when you work in a very corporate atmosphere).
The only issue I would say I have is that one needs to re-apply often. It might just be me but I do go through a tube in a short amount of time because of it...Still worth it though :)